Muscle Morphology, Mechanics, and Performance Laboratory
University of Colorado :: RMR VAMC :: ECHS GRECC
///////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////
Completed 3MAP Lab Projects...
MUSCLED
Prototype Development
& Pilot Study
Study Brochure
UL1TR000075, NIH CTSA (GW- Children’s National) - Innovative Strategies and Services Voucher Award
DiPietro, Loretta (PI)
Ismail, Catheeja (Co-PI)
Harris-Love, Michael (Co-PI)
Sarcopenia Screening: Development of a Feedback-Augmented, Portable, Ultrasound Prototype
This project involves the design and fabrication of a 2nd generation prototype ultrasound stabilization arm augmented with computer-assisted feedback. Our team seeks to better control the orientation of the ultrasound transducer to control the operator-dependent factors that may influence image quality and tissue dimensions in clinical settings. This work will extend to multiple projects at GW and the DC VAMC.
Co-Investigators:
Dr. Blackman, Dr. Garra, Dr. Hernandez, Dr. Lunsford, and Ms. Zabal
Study information:
https://clinicaltrials.gov/show/NCT02319850
VISN 5 Pilot Research Grant (VISN 5; VA Station: 688), VHA/VA Capitol Health Care Network
Harris-Love, Michael (PI)
Creating a Model of Proactive Geriatric Care within VISN 5:
Screening for Age-Related Skeletal Muscle Dysfunction at the Washington DC VA Medical Center
Determine if a rapid, mobile, cost-effective, screening method for assessing muscle mass and quality is appropriate for Veterans with comorbid conditions, and be portable to VA community-based outpatient clinics.
Co-Investigators:
Dr. Blackman, Dr. Taub, Dr. Hesdorffer, Dr. Garra, Dr. Hernandez, and Ms. Adams
Study information:
https://clinicaltrials.gov/ct2/show/NCT02277236
Negative Work Training and Knee Osteoarthritis
38 U.S.C. 7406, VA/ORD/RR&D-OAA
Harris-Love, Michael (PI and Research Mentor)
Development of a Negative Work Exercise Regimen as an Intervention for Posttraumatic Osteoarthritis of the Knee
The purpose of this randomized controlled clinical trial is to develop a safe and effective paradigm of negative work training appropriate for the rehabilitation of knee PTOA.
Interprofessional Polytrauma and Traumatic Brain Injury Rehabilitation Research Fellowship - Lead Investigator: Dr. Haniel Hernandez
Study information:
http://clinicaltrials.gov/show/NCT02098096

The ULTRA Study
Cross-Comparison of Muscle Composition Measures in Multiple Ultrasound Systems
(38 U.S.C. 7406; IK2RX001854-01)
Harris-Love, Michael (PI)
Gonzales,Tomas (Co-I)
Hernandez, Haniel (Co-I)
Few techniques have been proposed to reliably compare quantitative morphometry and morphology measures across ultrasound systems. Development of new cross-comparison methods could expand quantitative musculoskeletal ultrasound applications and improve neuromuscular symptoms diagnosis.The purpose of this study is to develop computational methods for cross-comparison of proxy muscle composition measurements in three laboratory ultrasound systems. This cross-sectional study will be conducted using the ultrasound images of selected muscles in Veteran participants. These data will be used to develop conversion models for each system.
Study information:
https://clinicaltrials.gov/show/NCT02920619