Negative Work Training and Knee Osteoarthritis
38 U.S.C. 7406, VA/ORD/RR&D-OAA
Harris-Love, Michael (PI and Research Mentor)
Development of a Negative Work Exercise Regimen as an Intervention for Posttraumatic Osteoarthritis of the Knee
The purpose of this randomized controlled clinical trial is to develop a safe and effective paradigm of negative work training appropriate for the rehabilitation of knee PTOA.
Interprofessional Polytrauma and Traumatic Brain Injury Rehabilitation Research Fellowship - Lead Investigator: Dr. Haniel Hernandez
The Age-Related Skeletal Muscle Dysfunction Study II (The ARMS Study II)
A 5-year collaborative study at the DC VAMC and Howard University involving African Americans featuring musculoskeletal assessment and strengthening exercise.
IK2RX001854-01, VA/ORD/RR&D (DC VAMC-Howard University)
Harris-Love, Michael (PI)
Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans (ARMS-II)
The objectives of this study are to: 1) validate a rapid, portable, cost-effective method for characterizing muscle size and quality using diagnostic ultrasound in younger and older adults, and 2) investigate a novel approach to progressive resistance exercise involving eccentric muscle actions that will counter the local effects of myosteatosis and sarcopenia in African Americans.
Dr. Blackman, Dr. Vernon Bond, Dr. Taub, Mr. Pennington, Ms. McIntosh, Mr. Hoover, and Mr. Gonzales
The QUALITy-VETS Project
VA Spark-Seed-Spread Innovation Program:
Quantitative Ultrasound Assessment of Lean and Intramuscular Adipose Tissue in Veterans Project (The QUALITy-VETS Project; AM-251 12-11-2015 and UL1TR000101)
Harris-Love, Michael (Co-PI, DC VAMC Site)
Delgado, Cynthia (Co-PI, SF VAMC Site)
Veterans have chronic kidney disease (CKD) prevalence estimates 35% higher than that of the general population. Importantly, CKD is associated with progressive muscle wasting and declining physical function.
The QUALITy-VETS Project is a joint patient care improvement initiative by the DC VAMC and the SF VAMC, informed by the human-centered design process, which promotes sarcopenia screening among Veterans with CKD. Key study objectives include identifying Veterans with CKD at risk for incident mobility limitations, and determining a pragmatic strategy to integrate sarcopenia screening into the baseline assessment.
3MAP Lab - Appointments: 202-745-8000 x55852
The ULTRA Study
Cross-Comparison of Muscle Composition Measures in Multiple Ultrasound Systems
(38 U.S.C. 7406; IK2RX001854-01)
Harris-Love, Michael (PI)
Hernandez, Haniel (Co-I)
Few techniques have been proposed to reliably compare quantitative morphometry and morphology measures across ultrasound systems. Development of new cross-comparison methods could expand quantitative musculoskeletal ultrasound applications and improve neuromuscular symptoms diagnosis.The purpose of this study is to develop computational methods for cross-comparison of proxy muscle composition measurements in three laboratory ultrasound systems. This cross-sectional study will be conducted using the ultrasound images of selected muscles in Veteran participants. These data will be used to develop conversion models for each system.